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3-Acetylpyridine Neurotoxicity in Mice
3-acetylpyridine (3-AP) is a metabolic antagonist used in research to decrease levels of nicotinamide (niacinamide) in laboratory animals. The administration of 3-AP followed by nicotinamide to rats leads to the selective destruction of neurons in the medial inferior olive, resulting in a loss of cl...
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| Publicado no: | Neurotoxicology |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5303548/ https://ncbi.nlm.nih.gov/pubmed/27986589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2016.11.010 |
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