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Epstein-Barr nuclear antigen 1 mediates a DNA loop within the latent replication origin of Epstein-Barr virus.

Epstein-Barr virus-encoded nuclear antigen 1 (EBNA-1) binds and activates the viral latent origin of DNA replication, oriP. We have used electron microscopy to examine the assembly of EBNA-1 onto oriP. The oriP region consists of two essential elements separated by approximately 1 kilobase pair of D...

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Main Authors: Frappier, L, O'Donnell, M
格式: Artigo
語言:Inglês
出版: 1991
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC53034/
https://ncbi.nlm.nih.gov/pubmed/1660154
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