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Leveraging genome-wide datasets to quantify the functional role of the anti-Shine–Dalgarno sequence in regulating translation efficiency

Studies dating back to the 1970s established that sequence complementarity between the anti-Shine–Dalgarno (aSD) sequence on prokaryotic ribosomes and the 5′ untranslated region of mRNAs helps to facilitate translation initiation. The optimal location of aSD sequence binding relative to the start co...

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Bibliografiske detaljer
Udgivet i:Open Biol
Main Authors: Hockenberry, Adam J., Pah, Adam R., Jewett, Michael C., Amaral, Luís A. N.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303271/
https://ncbi.nlm.nih.gov/pubmed/28100663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160239
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