Human U87 glioblastoma cells with stemness features display enhanced sensitivity to natural killer cell cytotoxicity through altered expression of NKG2D ligand

BACKGROUND: Glioblastoma (GBM) is one of the most lethal tumors with a poor prognosis. Its inevitable recurrence is frequently explained by the presence of cancer stem cells. We aimed to show that human GBM cells with stemness features are more sensitive to natural killer (NK) cells than GBM cells w...

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Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Oh, Se-Jeong, Yang, Jung-In, Kim, Ok, Ahn, Eun-Jung, Kang, Woo Dae, Lee, Jae-Hyuk, Moon, Kyung-Sub, Lee, Kyung-Hwa, Cho, Duck
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Primary Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303255/
https://ncbi.nlm.nih.gov/pubmed/28203118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-017-0397-7
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