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Fulvestrant inhibits growth of triple negative breast cancer and synergizes with tamoxifen in ERα positive breast cancer by up-regulation of ERβ

The estrogen receptor-alpha (ERα) is used as a predictive marker for anti-estrogen therapy in breast cancer patients. In addition to aromatase inhibitors, ERα can be targeted at the receptor level using the receptor modulator tamoxifen or by the pure anti-estrogen fulvestrant. The role of the second...

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Pubblicato in:Oncotarget
Autori principali: Mishra, Ameet K., Abrahamsson, Annelie, Dabrosin, Charlotta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302959/
https://ncbi.nlm.nih.gov/pubmed/27486755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10871
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