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Efficient transformation of cam2, a behavioral mutant of Paramecium tetraurelia, with the calmodulin gene.

An Ile-136----Thr substitution in calmodulin reduces the Ca(2+)-dependent K+ currents of cam2, a behavioral mutant of Paramecium tetraurelia, and renders it overly susceptible to BaCl2. DNA fragments carrying the wild-type CAM gene injected into cam2 macronuclei reverted these phenotypes in the clon...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kanabrocki, J A, Saimi, Y, Preston, R R, Haynes, W J, Kung, C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53028/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1961754/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10845
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