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A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits

Shared genetic aetiology may explain the co-occurrence of diseases in individuals more often than expected by chance. On identifying associated variants shared between two traits, one objective is to determine whether such overlap may be explained by specific genomic characteristics (eg, functional...

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Bibliografske podrobnosti
izdano v:Eur J Hum Genet
Main Authors: Asimit, Jennifer L, Payne, Felicity, Morris, Andrew P, Cordell, Heather J, Barroso, Inês
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302181/
https://ncbi.nlm.nih.gov/pubmed/28000695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.171
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