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Acetate fluxes in Escherichia coli are determined by the thermodynamic control of the Pta-AckA pathway

Escherichia coli excretes acetate upon growth on fermentable sugars, but the regulation of this production remains elusive. Acetate excretion on excess glucose is thought to be an irreversible process. However, dynamic (13)C-metabolic flux analysis revealed a strong bidirectional exchange of acetate...

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Pubblicato in:Sci Rep
Autori principali: Enjalbert, Brice, Millard, Pierre, Dinclaux, Mickael, Portais, Jean-Charles, Létisse, Fabien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301487/
https://ncbi.nlm.nih.gov/pubmed/28186174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42135
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