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Case report: rapid and durable response to PDGFR targeted therapy in a child with refractory multiple infantile myofibromatosis and a heterozygous germline mutation of the PDGFRB gene

BACKGROUND: Infantile myofibromatosis belongs to a family of soft tissue tumors. The majority of these tumors have benign behavior but resistant and malignant courses are known, namely in tumors with visceral involvement. The standard of care is surgical resection. Observations suggest that low dose...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Mudry, Peter, Slaby, Ondrej, Neradil, Jakub, Soukalova, Jana, Melicharkova, Kristyna, Rohleder, Ondrej, Jezova, Marta, Seehofnerova, Anna, Michu, Elleni, Veselska, Renata, Sterba, Jaroslav
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301362/
https://ncbi.nlm.nih.gov/pubmed/28183292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3115-x
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