Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model

This study was aimed to evaluate the effects of celastrol, a natural compound with multiple bioactivities, on multiple sclerosis and optic neuritis (ON) in rat experimental autoimmune encephalomyelitis (EAE). EAE was induced in Sprague Dawley rats using myelin basic protein, and the animals received...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Yang, Hongbin, Liu, Chang, Jiang, Jie, Wang, Yuena, Zhang, Xiaoyu
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301323/
https://ncbi.nlm.nih.gov/pubmed/28239352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00044
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