Granulocyte Macrophage Colony-Stimulating Factor–Activated CD39(+)/CD73(+) Murine Monocytes Modulate Intestinal Inflammation via Induction of Regulatory T Cells

BACKGROUND & AIMS: Granulocyte macrophage colony-stimulating factor (GM-CSF) treatment induces clinical response in patients with active Crohn’s disease. To explore whether monocytes mediate GM-CSF effects in vivo, we used a mouse model of chronic colitis induced by dextran sulfate sodium (DSS)....

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Weinhage, Toni, Däbritz, Jan, Brockhausen, Anne, Wirth, Timo, Brückner, Markus, Belz, Michael, Foell, Dirk, Varga, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301274/
https://ncbi.nlm.nih.gov/pubmed/28210690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.04.005
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