B10 Cell Frequencies and Suppressive Capacity in Myasthenia Gravis Are Associated with Disease Severity

Myasthenia gravis (MG) is a T cell-dependent, B cell-mediated disease. The mechanisms for loss of self-tolerance in this disease are not well understood, and recently described regulatory B cell (Breg) subsets have not been thoroughly investigated. B10 cells are a subset of Bregs identified by the p...

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Foilsithe in:Front Neurol
Main Authors: Yi, John S., Russo, Melissa A., Massey, Janice M., Juel, Vern, Hobson-Webb, Lisa D., Gable, Karissa, Raja, Shruti M., Balderson, Kristina, Weinhold, Kent J., Guptill, Jeffrey T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2017
Ábhair:
Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301008/
https://ncbi.nlm.nih.gov/pubmed/28239367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00034
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