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Interference between Triplex and Protein Binding to Distal Sites on Supercoiled DNA
We have explored the interdependence of the binding of a DNA triplex and a repressor protein to distal recognition sites on supercoiled DNA minicircles using MD simulations. We observe that the interaction between the two ligands through their influence on their DNA template is determined by a subtl...
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| Publicado en: | Biophys J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5300792/ https://ncbi.nlm.nih.gov/pubmed/28108011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.12.034 |
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