Immunizations of monkeys with synthetic peptides disclose conserved areas on gp120 of human immunodeficiency virus type 1 associated with cross-neutralizing antibodies and T-cell recognition.

Site-directed immunization was employed to identify sites on the envelope glycoprotein gp120 for antibody-mediated neutralization of human immunodeficiency virus type 1 (HIV-1). Antisera were raised in monkeys (Macaca fascicularis) against a series of 40 overlapping synthetic peptides covering the e...

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Bibliographische Detailangaben
Hauptverfasser: Vahlne, A, Horal, P, Eriksson, K, Jeansson, S, Rymo, L, Hedström, K G, Czerkinsky, C, Holmgren, J, Svennerholm, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC53007/
https://ncbi.nlm.nih.gov/pubmed/1961741
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