Rikkunshito prevents paclitaxel-induced peripheral neuropathy through the suppression of the nuclear factor kappa B (NFκB) phosphorylation in spinal cord of mice

Peripheral neuropathy is the major side effect caused by paclitaxel, a microtubule-binding antineoplastic drug. Paclitaxel-induced peripheral neuropathy causes a long-term negative impact on the patient's quality of life. However, the mechanism underlying paclitaxel-induced peripheral neuropath...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Kamei, Junzo, Hayashi, Shunsuke, Sakai, Akane, Nakanishi, Yuki, Kai, Misa, Ikegami, Megumi, Ikeda, Hiroko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300261/
https://ncbi.nlm.nih.gov/pubmed/28182729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171819
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