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Biochemical and biophysical investigations of the interaction between human glucokinase and pro-apoptotic BAD
The glycolytic enzyme glucokinase (GCK) and the pro-apoptotic protein BAD reportedly reside within a five-membered complex that localizes to the mitochondria of mammalian hepatocytes and pancreatic β-cells. Photochemical crosslinking studies using a synthetic analog of BAD’s BH3 domain and in vitro...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5300155/ https://ncbi.nlm.nih.gov/pubmed/28182770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171587 |
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