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The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo
Mammalian development begins with segregation of the extra-embryonic trophectoderm from the embryonic lineage in the blastocyst. While cell polarity and adhesion play key roles, the decisive cue driving this lineage segregation remains elusive. Here, to study symmetry breaking, we use a reduced syst...
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| Publicat a: | Dev Cell |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5300053/ https://ncbi.nlm.nih.gov/pubmed/28171747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.01.006 |
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