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Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src.

Phosphorylation of the carboxyl terminus of pp60c-src, the product of the c-src protooncogene, at Tyr-527 suppresses its tyrosine kinase activity and transforming potential. It has been proposed that the phosphorylated carboxyl terminus of pp60c-src inhibits kinase activity by binding to the SH2 (sr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Roussel, R R, Brodeur, S R, Shalloway, D, Laudano, A P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1991
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC52997/
https://ncbi.nlm.nih.gov/pubmed/1720546
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