Differences in the transcriptome of medullary thyroid cancer regarding the status and type of RET gene mutations

Medullary thyroid cancer (MTC) can be caused by germline mutations of the RET proto-oncogene or occurs as a sporadic form. It is well known that RET mutations affecting the cysteine-rich region of the protein (MEN2A-like mutations) are correlated with different phenotypes than those in the kinase do...

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Udgivet i:Sci Rep
Main Authors: Oczko-Wojciechowska, Malgorzata, Swierniak, Michal, Krajewska, Jolanta, Kowalska, Malgorzata, Kowal, Monika, Stokowy, Tomasz, Wojtas, Bartosz, Rusinek, Dagmara, Pawlaczek, Agnieszka, Czarniecka, Agnieszka, Szpak-Ulczok, Sylwia, Gawlik, Tomasz, Chmielik, Ewa, Tyszkiewicz, Tomasz, Nikiel, Barbara, Lange, Dariusz, Jarzab, Michal, Wiench, Malgorzata, Jarzab, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299608/
https://ncbi.nlm.nih.gov/pubmed/28181547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42074
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