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Calpain-Mediated Proteolysis of Talin and FAK Regulates Adhesion Dynamics Necessary for Axon Guidance

Guidance of axons to their proper synaptic target sites requires spatially and temporally precise modulation of biochemical signals within growth cones. Ionic calcium (Ca(2+)) is an essential signal for axon guidance that mediates opposing effects on growth cone motility. The diverse effects of Ca(2...

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Pubblicato in:J Neurosci
Autori principali: Kerstein, Patrick C., Patel, Kevin M., Gomez, Timothy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299572/
https://ncbi.nlm.nih.gov/pubmed/28069919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2769-16.2016
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