Protective effect of mangiferin on myocardial ischemia-reperfusion injury in streptozotocin-induced diabetic rats: role of AGE-RAGE/MAPK pathways

Hyperglycemia induced advanced glycation end products-receptor for advanced glycation end products (AGE-RAGE) activation is thought to involve in the development of cardiovascular disease in diabetics. Activation of AGE-RAGE axis results in the oxidative stress and inflammation. Mangiferin is found...

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Published in:Sci Rep
Main Authors: Suchal, Kapil, Malik, Salma, Khan, Sana Irfan, Malhotra, Rajiv Kumar, Goyal, Sameer N., Bhatia, Jagriti, Kumari, Santosh, Ojha, Shreesh, Arya, Dharamvir Singh
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299420/
https://ncbi.nlm.nih.gov/pubmed/28181586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42027
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