Functional and Antigen-Specific Serum Antibody Levels as Correlates of Protection against Shigellosis in a Controlled Human Challenge Study

Shigella is an important cause of diarrheal disease in young children living in developing countries. No approved vaccines are available, and the development of vaccine candidates has been hindered by the lack of firm immunological correlates of protection, among other reasons. To address this gap i...

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Pubblicato in:Clin Vaccine Immunol
Autori principali: Shimanovich, Avital A., Buskirk, Amanda D., Heine, Shannon J., Blackwelder, William C., Wahid, Rezwanul, Kotloff, Karen L., Pasetti, Marcela F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Clinical Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299116/
https://ncbi.nlm.nih.gov/pubmed/27927680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00412-16
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