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Dexamethasone Inhibits S. aureus-Induced Neutrophil Extracellular Pathogen-Killing Mechanism, Possibly through Toll-Like Receptor Regulation

Neutrophils release neutrophil extracellular traps (NETs) in a pathogen-killing process called NETosis. Excessive NETs formation, however, is implicated in disease pathogenesis. Therefore, to understand how NETosis is regulated, we examined the effect of dexamethasone (DXM), an anti-inflammatory dru...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Wan, Ting, Zhao, Yingying, Fan, Fangli, Hu, Renjian, Jin, Xiuming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299007/
https://ncbi.nlm.nih.gov/pubmed/28232829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00060
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