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CD10/neutral endopeptidase 24.11 hydrolyzes bombesin-like peptides and regulates the growth of small cell carcinomas of the lung.

Bombesin-like peptides are essential autocrine growth factors for many small cell carcinomas (SCCas) of the lung. Herein, we demonstrate that these malignant pulmonary neuroendocrine cells express low levels of the cell surface metalloendopeptidase CD10/neutral endopeptidase 24.11 (CD10/NEP, common...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Shipp, M A, Tarr, G E, Chen, C Y, Switzer, S N, Hersh, L B, Stein, H, Sunday, M E, Reinherz, E L
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52990/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1660144/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10662
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