Physicochemical Characterization of Ferumoxytol, Heparin and Protamine Nanocomplexes for improved magnetic labeling of stem cells

Stem cell-based therapies have become a major focus in regenerative medicine and to treat diseases. A straightforward approach combining three drugs, heparin (H), protamine (P) with ferumoxytol (F) in the form of nanocomplexes (NCs) effectively labeled stem cells for cellular MRI. We report on the p...

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Veröffentlicht in:Nanomedicine
Hauptverfasser: Bryant, L. Henry, Kim, Saejeong J., Hobson, Matthew, Milo, Blerta, Kovacs, Zsofia I, Jikiria, Neekita, Lewis, Bobbi K., Aronova, Maria A., Sousa, Alioscka A., Zhang, Guofeng, Leapman, Richard D., Frank, Joseph A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298948/
https://ncbi.nlm.nih.gov/pubmed/27520728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2016.07.011
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