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My Cousin, My Enemy: quasispecies suppression of drug resistance

If a freshly minted genome contains a mutation that confers drug resistance, will it be selected in the presence of the drug? Not necessarily. During viral infections, newly synthesized viral genomes occupy the same cells as parent and other progeny genomes. If the antiviral target is chosen so that...

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Detalhes bibliográficos
Publicado no:Curr Opin Virol
Main Authors: Kirkegaard, Karla, van Buuren, Nicholas J, Mateo, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298929/
https://ncbi.nlm.nih.gov/pubmed/27764731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2016.09.011
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