Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1

HIV-1 particles assemble and bud from the plasma membrane of infected T lymphocytes. Infected macrophages, in contrast, accumulate particles within an apparent intracellular compartment known as the virus-containing compartment or VCC. Many aspects of the formation and function of the VCC remain unc...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Hammonds, Jason E., Beeman, Neal, Ding, Lingmei, Takushi, Sarah, Francis, Ashwanth C., Wang, Jaang-Jiun, Melikyan, Gregory B., Spearman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298340/
https://ncbi.nlm.nih.gov/pubmed/28129379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006181
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