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Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation

Fibroblast growth factor 19 (FGF19) is a gut-derived peptide hormone that is produced following activation of Farnesoid X Receptor (FXR). FGF19 is secreted and signals to the liver, where it contributes to the homeostasis of bile acid (BA), lipid and carbohydrate metabolism. FGF19 is a promising the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Massafra, Vittoria, Milona, Alexandra, Vos, Harmjan R., Burgering, Boudewijn M. T., van Mil, Saskia W. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298232/
https://ncbi.nlm.nih.gov/pubmed/28178326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171185
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