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Mic60/Mitofilin Overexpression Alters Mitochondrial Dynamics and Attenuates Vulnerability of Dopaminergic Cells to Dopamine and Rotenone

Mitochondrial dysfunction has been implicated in Parkinson’s disease (PD) neuropathology. Mic60, also known as mitofilin, is a protein of the inner mitochondrial membrane and a key component of the mitochondrial contact site and cristae junction organizing system (MICOS). Mic60 is critical for maint...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neurobiol Dis
Main Authors: Van Laar, Victor S., Berman, Sarah B., Hastings, Teresa G.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298082/
https://ncbi.nlm.nih.gov/pubmed/27001148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.03.015
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