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Pharmacokinetics of Lidocaine and Its Metabolites Following Vaginal Administration of Lidocaine Gel to Healthy Female Subjects

Lidocaine vaginal bioadhesive gel is being developed as a local anesthetic for use in minimally invasive outpatient gynecological procedures and was investigated in single‐dose and multiple‐dose studies in healthy young adult women. Lidocaine doses of 2.5%, 5%, and 10% (w/w) were administered, and p...

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Vydáno v:Clin Pharmacol Drug Dev
Hlavní autoři: Martell, Bridget, Kushner, Harvey, Richardson, Elaine, Mize, Amy, Mayer, Philip
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298036/
https://ncbi.nlm.nih.gov/pubmed/27297519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.286
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