Detection of genomic rearrangements from targeted resequencing data in Parkinson's disease patients

BACKGROUND: The analysis of coverage depth in next‐generation sequencing data allows the detection of gene dose alterations. We explore the frequency of such structural events in a Spanish cohort of sporadic PD cases. METHODS: Gene dose alterations were detected with the eXome‐Hidden Markov Model (X...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mov Disord
Auteurs principaux: Spataro, Nino, Roca‐Umbert, Ana, Cervera‐Carles, Laura, Vallès, Mònica, Anglada, Roger, Pagonabarraga, Javier, Pascual‐Sedano, Berta, Campolongo, Antònia, Kulisevsky, Jaime, Casals, Ferran, Clarimón, Jordi, Bosch, Elena
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Brief Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297984/
https://ncbi.nlm.nih.gov/pubmed/28124432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26845
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