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MicroRNA-29a Alleviates Bile Duct Ligation Exacerbation of Hepatic Fibrosis in Mice through Epigenetic Control of Methyltransferases

MicroRNA-29 (miR-29) is found to modulate hepatic stellate cells’ (HSCs) activation and, thereby, reduces liver fibrosis pathogenesis. Histone methyltransferase regulation of epigenetic reactions reportedly participates in hepatic fibrosis. This study is undertaken to investigate the miR-29a regulat...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yang, Ya-Ling, Wang, Feng-Sheng, Li, Sung-Chou, Tiao, Mao-Meng, Huang, Ying-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297823/
https://ncbi.nlm.nih.gov/pubmed/28106784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010192
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