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Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/β-Catenin Pathway

Mechanical loading and hydrostatic pressure (HP) regulate chondrocytes’ metabolism; however, how mechanical stimulation acts remain unclear. MicroRNAs (miRNAs) play an important role in cartilage homeostasis, mechanotransduction, and in the pathogenesis of osteoarthritis (OA). This study investigate...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cheleschi, Sara, De Palma, Anna, Pecorelli, Alessandra, Pascarelli, Nicola Antonio, Valacchi, Giuseppe, Belmonte, Giuseppe, Carta, Serafino, Galeazzi, Mauro, Fioravanti, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297766/
https://ncbi.nlm.nih.gov/pubmed/28085114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010133
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