Clinical Significance and Prognostic Relevance of Microsatellite Instability in Sporadic Colorectal Cancer Patients

Microsatellite instability (MSI) is a marker of the replication error phenotype. It is caused by impaired DNA mismatch repair processes (MMR), resulting in ineffectiveness of the mechanisms responsible for the DNA replication precision and postreplicative DNA repair. MSI underlies the pathogenesis o...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Copija, Angelika, Waniczek, Dariusz, Witkoś, Andrzej, Walkiewicz, Katarzyna, Nowakowska-Zajdel, Ewa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297741/
https://ncbi.nlm.nih.gov/pubmed/28067827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010107
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