Time-Dependent Nerve Growth Factor Signaling Changes in the Rat Retina During Optic Nerve Crush-Induced Degeneration of Retinal Ganglion Cells

Nerve growth factor (NGF) is suggested to be neuroprotective after nerve injury; however, retinal ganglion cells (RGC) degenerate following optic-nerve crush (ONC), even in the presence of increased levels of endogenous NGF. To further investigate this apparently paradoxical condition, a time-course...

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Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Mesentier-Louro, Louise A., De Nicolò, Sara, Rosso, Pamela, De Vitis, Luigi A., Castoldi, Valerio, Leocani, Letizia, Mendez-Otero, Rosalia, Santiago, Marcelo F., Tirassa, Paola, Rama, Paolo, Lambiase, Alessandro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297732/
https://ncbi.nlm.nih.gov/pubmed/28067793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010098
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