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A one-step matrix application method for MALDI mass spectrometry imaging of bacterial colony biofilms

MALDI imaging of biofilms cultured on agar plates is challenging because of problems related to matrix deposition onto agar. We describe a one-step, spray-based application of a 2,5-dihydroxybenzoic acid solution for direct MALDI imaging of hydrated Bacillus subtilis biofilms on agar. Using both an...

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Detalhes bibliográficos
Publicado no:J Mass Spectrom
Main Authors: Li, Bin, Comi, Troy J., Si, Tong, Dunham, Sage J. B., Sweedler, Jonathan V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297451/
https://ncbi.nlm.nih.gov/pubmed/27476992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.3827
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