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Combining varenicline (Chantix) with naltrexone decreases alcohol drinking more effectively than does either drug alone in a rodent model of alcoholism

BACKGROUND: This study examined whether varenicline (VAR), or naltrexone (NTX), alone or in combination, reduces alcohol drinking in alcohol-preferring (P) rats with a genetic predisposition toward high voluntary alcohol intake. METHODS: Alcohol experienced P rats that had been drinking alcohol (15%...

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Опубликовано в: :Alcohol Clin Exp Res
Главные авторы: Froehlich, Janice C., Fischer, Stephen M., Dilley, Julian E., Nicholson, Emily, Smith, Teal, Filosa, Nick, Rademacher, Logan
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297249/
https://ncbi.nlm.nih.gov/pubmed/27469281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13157
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