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Prazosin + naltrexone decreases alcohol drinking more effectively than does either drug alone in P rats with a protracted history of extensive voluntary alcohol drinking, dependence and multiple withdrawals
BACKGROUND: Prazosin (PRZ, an α(1)-adrenergic receptor antagonist) and naltrexone (NTX, a non-specific opioid receptor antagonist) each decrease alcohol drinking when administered to rats selectively-bred for high voluntary alcohol drinking (alcohol-preferring, or “P”), and the combination of PRZ+NT...
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| Publicado no: | Alcohol Clin Exp Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558320/ https://ncbi.nlm.nih.gov/pubmed/26260061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12828 |
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