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Branched-Chain in situ Hybridization for κ and λ Light Chains: A Powerful Ancillary Technique for Determining B-Cell Clonality in Cytology Samples

BACKGROUND: Current immunohistochemical and in situ hybridization (ISH) assays are generally inconclusive for clonality unless plasmacytic differentiation is present. This study examined a series of cytology specimens and explored the ability of a branched-chain RNA (bRNA) ISH assay for immunoglobul...

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Bibliografiske detaljer
Udgivet i:Cancer Cytopathol
Main Authors: Arora, Kshitij, Chebib, Ivan, Zukerberg, Lawrence, Gandhi, Manoj, Rivera, Miguel, Ting, David, Deshpande, Vikram
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296944/
https://ncbi.nlm.nih.gov/pubmed/26524200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncy.21629
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