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Targeting the molecular chaperone SlyD to inhibit bacterial growth with a small molecule

Molecular chaperones are essential molecules for cell growth, whereby they maintain protein homeostasis. Because of their central cellular function, bacterial chaperones might be potential candidates for drug targets. Antimicrobial resistance is currently one of the greatest threats to human health,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kumar, Amit, Balbach, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296862/
https://ncbi.nlm.nih.gov/pubmed/28176839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42141
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