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Structural basis for redox sensitivity in Corynebacterium glutamicum diaminopimelate epimerase: an enzyme involved in l-lysine biosynthesis

Diaminopimelate epimerase (DapF) is one of the crucial enzymes involved in l-lysine biosynthesis, where it converts l,l-diaminopimelate (l,l-DAP) into d,l-DAP. DapF is also considered as an attractive target for the development of antibacterial drugs. Here, we report the crystal structure of DapF fr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sagong, Hye-Young, Kim, Kyung-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296763/
https://ncbi.nlm.nih.gov/pubmed/28176858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42318
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