HOPX hypermethylation promotes metastasis via activating SNAIL transcription in nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is characterized by a high rate of local invasion and early distant metastasis. Increasing evidence indicates that epigenetic abnormalities play important roles in NPC development. However, the epigenetic mechanisms underlying NPC metastasis remain unclear. Here we inv...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Ren, Xianyue, Yang, Xiaojing, Cheng, Bin, Chen, Xiaozhong, Zhang, Tianpeng, He, Qingmei, Li, Bin, Li, Yingqin, Tang, Xinran, Wen, Xin, Zhong, Qian, Kang, Tiebang, Zeng, Musheng, Liu, Na, Ma, Jun
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296651/
https://ncbi.nlm.nih.gov/pubmed/28146149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14053
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