HOPX hypermethylation promotes metastasis via activating SNAIL transcription in nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is characterized by a high rate of local invasion and early distant metastasis. Increasing evidence indicates that epigenetic abnormalities play important roles in NPC development. However, the epigenetic mechanisms underlying NPC metastasis remain unclear. Here we inv...

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Foilsithe in:Nat Commun
Main Authors: Ren, Xianyue, Yang, Xiaojing, Cheng, Bin, Chen, Xiaozhong, Zhang, Tianpeng, He, Qingmei, Li, Bin, Li, Yingqin, Tang, Xinran, Wen, Xin, Zhong, Qian, Kang, Tiebang, Zeng, Musheng, Liu, Na, Ma, Jun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296651/
https://ncbi.nlm.nih.gov/pubmed/28146149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14053
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