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Synthesis of Indole-2-carboxylate Derivatives via Palladium-catalyzed Aerobic Amination of Aryl C–H Bonds
A direct oxidative C–H amination to 1-acetyl indole-carboxylates is achieved starting from 2-acetamido-3-aryl-acrylates. Indole-2-carboxylates can be targeted with a straightforward deacetylation of the initial reaction product. The C–H amination reaction is carried out using a catalytic Pd(II) sour...
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| Publicado en: | Org Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5296645/ https://ncbi.nlm.nih.gov/pubmed/27404018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b01592 |
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