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Selective Whole-Genome Amplification Is a Robust Method That Enables Scalable Whole-Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples

Whole-genome sequencing (WGS) of microbial pathogens from clinical samples is a highly sensitive tool used to gain a deeper understanding of the biology, epidemiology, and drug resistance mechanisms of many infections. However, WGS of organisms which exhibit low densities in their hosts is challengi...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Cowell, Annie N., Loy, Dorothy E., Sundararaman, Sesh A., Valdivia, Hugo, Fisch, Kathleen, Lescano, Andres G., Baldeviano, G. Christian, Durand, Salomon, Gerbasi, Vince, Sutherland, Colin J., Nolder, Debbie, Vinetz, Joseph M., Hahn, Beatrice H., Winzeler, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296604/
https://ncbi.nlm.nih.gov/pubmed/28174312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02257-16
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