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Pif1-family helicases cooperate to suppress widespread replication fork arrest at tRNA genes

Saccharomyces cerevisiae encodes two distinct Pif1-family helicases – Pif1 and Rrm3 – which have been reported to play distinct roles in numerous nuclear processes. Here, we systematically characterize the roles of Pif1 helicases in replisome progression and lagging-strand synthesis in S. cerevisiae...

詳細記述

保存先:
書誌詳細
出版年:Nat Struct Mol Biol
主要な著者: Osmundson, Joseph S., Kumar, Jayashree, Yeung, Rani, Smith, Duncan J.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296403/
https://ncbi.nlm.nih.gov/pubmed/27991904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3342
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