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Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease.

The relationship between Alzheimer disease (AD) and aging is not currently known. In this study, postmortem frontal- and occipital-pole brain samples were obtained from 16 subjects with AD, 8 age-matched controls, and 5 young controls. These samples were analyzed both for protein oxidation products...

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Detalhes bibliográficos
Main Authors: Smith, C D, Carney, J M, Starke-Reed, P E, Oliver, C N, Stadtman, E R, Floyd, R A, Markesbery, W R
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC52964/
https://ncbi.nlm.nih.gov/pubmed/1683703
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