Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease.

The relationship between Alzheimer disease (AD) and aging is not currently known. In this study, postmortem frontal- and occipital-pole brain samples were obtained from 16 subjects with AD, 8 age-matched controls, and 5 young controls. These samples were analyzed both for protein oxidation products...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Smith, C D, Carney, J M, Starke-Reed, P E, Oliver, C N, Stadtman, E R, Floyd, R A, Markesbery, W R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52964/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1683703/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10540
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