Reduction of Relapse after Unrelated Donor Stem Cell Transplantation by KIR-Based Graft Selection

Besides donor T cells, natural killer (NK) cells are considered to have a major role in preventing relapse after allogeneic hematopoietic stem cell transplantation (HSCT). After T-cell-depleted haploidentical HSCT, a strong NK alloreactivity has been described. These effects have been attributed to...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Heidenreich, Silke, Kröger, Nicolaus
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296332/
https://ncbi.nlm.nih.gov/pubmed/28228753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00041
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