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Membrane skeletal association and post-translational allosteric regulation of Toxoplasma gondii GAPDH1

When Toxoplasma gondii egresses from the host cell, glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH1), which is primary a glycolysis enzyme but actually a quintessential multifunctional protein, translocates to the unique cortical membrane skeleton. Here we report the 2.25Å resolution crystal stru...

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Bibliographic Details
Published in:Mol Microbiol
Main Authors: Dubey, Rashmi, Staker, Bart L., Foe, Ian T., Bogyo, Matthew, Myler, Peter J., Ngô, Huân M., Gubbels, Marc-Jan
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296235/
https://ncbi.nlm.nih.gov/pubmed/27859784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13577
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