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Extensive Functional Redundancy in the Regulation of Candida albicans Drug Resistance and Morphogenesis by Lysine Deacetylases Hos2, Hda1, Rpd3, and Rpd31

Current treatment efforts for fungal infections are hampered by the limited availability of antifungal drugs and by the emergence of drug resistance. A powerful strategy to enhance the efficacy of antifungal drugs is to inhibit the molecular chaperone Hsp90. Hsp90 governs drug resistance, morphogene...

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Détails bibliographiques
Publié dans:Mol Microbiol
Auteurs principaux: Li, Xinliu, Robbins, Nicole, O’Meara, Teresa R., Cowen, Leah E.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296215/
https://ncbi.nlm.nih.gov/pubmed/27868254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13578
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