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Extensive Functional Redundancy in the Regulation of Candida albicans Drug Resistance and Morphogenesis by Lysine Deacetylases Hos2, Hda1, Rpd3, and Rpd31

Current treatment efforts for fungal infections are hampered by the limited availability of antifungal drugs and by the emergence of drug resistance. A powerful strategy to enhance the efficacy of antifungal drugs is to inhibit the molecular chaperone Hsp90. Hsp90 governs drug resistance, morphogene...

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Publicado en:Mol Microbiol
Autores principales: Li, Xinliu, Robbins, Nicole, O’Meara, Teresa R., Cowen, Leah E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296215/
https://ncbi.nlm.nih.gov/pubmed/27868254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13578
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