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The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia

While cancer has been long recognized as a disease of the genome, the importance of epigenetic mechanisms in neoplasia was acknowledged more recently. The most active epigenetic marks are DNA methylation and histone protein modifications and they are involved in basic biological phenomena in every c...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Janczar, Szymon, Janczar, Karolina, Pastorczak, Agata, Harb, Hani, Paige, Adam J. W., Zalewska-Szewczyk, Beata, Danilewicz, Marian, Mlynarski, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295773/
https://ncbi.nlm.nih.gov/pubmed/28054944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9010002
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